By this point, it seemed like organoids with a living blood supply looked more like a human brain in terms of structure than they had ever looked in a dish because they were able to survive long enough to develop properly. However, the question still remained as to whether the neurons and their synapses were functional. Neurons are electrically excitable cells that receive, process and transmit information through electrical  and chemical signals. Calcium plays an important role in the transmission of electrical signals from one neuron to the next. Changes  in the levels of calcium at the end of neurons can be measured using calcium-sensing proteins that light up red. When the scientists looked through the glass window in the skulls of the mice, they were able to see that neurons did have fluctuating levels of calcium, suggesting that  neurons in the brain organoids were active. To be sure, they used electrodes to directly measure the electrical activity of the implanted organoid at different places and during different times of development, and discovered that the neurons were able to electrically stimulate each  other and respond to stimuli from the external environment.The researchers had succeeded in creating fully functional brain organoids. Then things got really interesting.
Magic happens with this amazingly deep meditation MP3. Delta stimulation can be very hypnotic, and Sub-Delta (0 – 1 Hz) in particular is theorized to have soothing effects on the limbic system, such as the amygdala and hypothalamus which themselves operate at delta frequencies. These neural structures are associated with emotions, fear, the fight-or-flight response, blood pressure, tension and more. Many people have found success using Delta as an aid in meditation. Using sub-delta to sooth these structures has resulted in amazing success helping health conditions such as fibromyalgia, chronic pain and hypertension (high blood pressure). Its soothing effects on the limbic system may shed some light on this.

Chronic fatigue: Subjective improvements in energy level may be reported by those who increase stimulatory beta and gamma waves. Fast waves tend to be associated with higher levels of arousal. Low arousal is associated with chronic fatigue and may be exacerbated by slow brain waves (e.g. theta and delta). As of now there aren’t any studies that have analyzed various protocols for their effect on a person’s energy or arousal.
Binaural beats are acoustically generated frequencies that match the frequency bands of brain waves and are therefore considered a means to inducing neurophysiological relaxation. There is, however, large dispute on the scientific quality and validity of extant research on binaural beats. Thus, the effect of a binaural 10Hz (Alpha) stimulation on subjective and physiological parameters ... [Show full abstract]Read more
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Two people with ADHD for example could have completely different ADHD subtypes. One could have inattentiveness as the primary symptom as a result of high theta waves, and the other could have high beta-2 waves as feel hyperactive. While generalized entrainment protocols should be studied, it is important to consider that each person may respond differently to the protocols; each person has a unique neural footprint.
I also believe that the dangers of brainwave entrainment should be further explored as well. There are relatively vague benefits, but it remains unclear as to whether entraining certain frequencies may be detrimental to performance or induce harm. Despite the fact that brainwave entrainment has existed for a long term, it remains an understudied niche in neuroscience.

Similar to how organisms and their genes compete for survival in the environment and gene pool, ideas compete for survival inside brains, and in the pool of ideas that inhabit them. The famous evolutionary biologist Richard Dawkins has used this insightful analogy to explain how ideas spread and evolve over time. In his influential 1976 book, "The Selfish Gene," he refers to ideas as “memes” (the mental analog of a gene), which he has defined as self-replicating units that spread throughout culture. We are all familiar with many types of memes, including the various customs, myths, and trends that have become part of human society.


I have also noticed that during my morning meditation session (I use the product twice daily – once in the morning and again at night), I’m able to almost instantly reach extremely deep levels of relaxation. In fact, within minutes I lose all sensation in my extremities. This is exactly like yogic meditation’s pratyahara, or sense withdrawal, state. It’s really quite remarkable that I could get that relaxed that quickly. This process usually takes me anywhere between a half an hour and an hour and a half. With EquiSync, I reach the same state in literally 2 to 5 minutes!
This session shifts from the 14Hz sensormotor rhythm through beta to 40Hz gamma, and repeats the pattern over and over, constantly “revving up”the mind with each repetition. The process is stabilized with a 10Hz background alpha beat, allowing the brain a place to relax instantly, whenever a let up allows. Use this session any time, and for as long as required to get the job done. Take in a High Energy Espresso on long-hauls for a welcome lift. Works without headphones, but the best benefits can be found with them. The session finishes at a fast, revving 18Hz beta. For use mainly with eyes open, engaged in activity - with benefit to be gained from periodically closing your eyes briefly and relaxing.
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