The  human brain is made up of billions of neurons which need to communicate in order for our brains to function as a whole. The point at which two neurons meet is called a synapse and chemical signals are transported between neurons, across these synapses. Not only were the scientists able to show that the transplanted organoids developed mature neurons,  but also that these neurons were able to form synapses with each other,  and with resident neurons in the mouse brain.
In simplest form, they are an audio technology which are used for (safe) brainwave entrainment. Our subconscious mind operates, throughout the day and night, in various brainwave state frequencies, measured in cycles per second (Hz) These frequencies range from the slowest (Delta) frequencies experienced in deep, dreamless sleep and in deep meditation where your conscious-awareness is fully detached, to the fastest (Gamma) frequencies associated to stimulating flow states, high-level thinking and information processing. There are actually 5 known brainwave state frequencies each having their own set of unique characteristics:
Practitioners are discovering a number of different areas in which entrainment therapy may bring positive benefits. From managing mental health more effectively through to providing increased mental focus and concentration, it is thought the technique can be adapted according to the specific issues being treated. An improved immune system, enhanced levels of pain management, and a reduction in autoimmune disorders are also thought to be achieved through the therapy, leading many individuals with chronic ill health to consider brainwave entrainment as a non-invasive yet effective therapy.
However, unlike our own brains, which last a lifetime, these mini-brains are relatively short-lived. The human brain has the advantage of a circulatory system, allowing it  to  survive and function. By supplying brain organoids with a special cocktail of factors, they can grow in a dish, develop and survive, but  only to a limited degree. But, by transplanting brain organoids into the brains of living mice, one group of scientists has shown that artificially grown organoids have the potential to resemble a real human brain even more closely when they  are sustained by a living blood supply.
Proceedings of the 9th Conference on Interdisciplinary Musicology – CIM14. Berlin, Germany 2014 first group it increases, and for the second decreases. Experimental group did not fall asleep but maintained a relaxation state after the stimulus, while control group achieved unconscious relaxation but the effects did not hold. The STAI “State” indicated that stress increased after the stimulus for control group (see graph A1.2). 14. CONCLUSIONS • Delta (20-200) and theta (20-100) brainwaves are the ones that have greater amplitude (microvolts) in both groups. Results are clearly shown in graphs A1.5 and A1.10. Graph A1.5 Theta Graph A1.10 Delta • Higher frequency EEG waves such as beta waves have less amplitude. This happens because they are not synchronized and have more phase differences in both groups. • An increased alpha parameter is higher in the experimental group, which indicates that they achieved conscious relaxation. In contrast, the control group showed higher delta waves and presented signs of deep sleep during the experiment. Control group also possibly reached REM (Rapid Eye Movement) sleep halfway throughout the stimulus due theta waves presence in the EEG. • Beta waves are higher in the control group from s = 507 to s = 624 because of unexpected sounds in the stimulus (traffic noise appeared in the original recording). • Both stimuli induced relaxation, but it is important to point out that a person can relax without falling asleep. In this way the binaural stimulus worked better. • It is likely that the control group fell asleep with the nature sounds stimuli because lack of stimulation. • Contrary to what we expected, theta binaural waves didn’t induced FFR in experimental group, although they helped to achieve conscious relaxation. • Delta waves were higher in the experimental group during post-experiment measurements. This suggests that relaxation states were maintained with the absence of stimulus. • Presence of Alpha waves was reduced during deep sleep. This evidence is supported by the control group’s Delta values. • In the absence of stimuli, Delta wave values of the control group decreased, which means that relaxation effects did not prevail. • The effectiveness of an anxiolytic may be measured through the relaxation degree during stimulus and whether its effect endured or not. • For further evaluation of coherence [17] between brainwaves in both hemispheres and the ERP, the use of a 10-20 EEG system is recommended. • Post-experimental STAI “State” tests results are lower in the experimental group. This means that Theta binaural waves were a better anxiolytic than the stimuli (nature sounds) used in the control group. REFERENCES [1] Huang, T., & Charyton, C. (2008). A Comprehensive Review of The Psychological Effects of Brainwave Entrainment. Alternative Therapies in Health and Medicine, 14(5). [2] Berger H. (1929) Über Das Elektrenkephalogramm Des Menschen. Arch Psychiatrie Nervenkrankheiten. [3] Chatrian GE, Petersen MC, Lazarte JA. (1960) Responses to clicks from the human brain: some depth electrographic observations. Electroenceph. Clin. Neurophysiol.. [4] Ulam, Frederick A. (1991) An Investigation of the effects of binaural beat frequencies on human brain waves. California School Of Professional Psychology. [5] Notimex. (2013, July 02). México, país con más estrés laboral. El Universal. Retrieved from: http://www.eluniversal.com.mx/ciencia/2013/mexico-pais-mas-estres-laboral-78744.html [6] American Psychological Association (n.d.). Stress: The different kinds of stress. Retrieved from: http://www.apa.org/helpcenter/stress-kinds.aspx [7] R. Padmanabhan, A. J. Hildreth and D. Laws. (2005) A prospective, randomised, experimentalled study examining binaural beat audio and pre-operative anxiety in patients undergoing general anaesthesia for day case surgery. Anaesthesia. 60, 769-773. [8] Loy, Gareth. (2006) Musimathics. London, England: MIT Press. [9] Atwater, F. Holmes. (2009) Frequency Following Response Study. The Monroe Institute. [10] Ferraro, Fernando M., Acuña, Marcelo. (n.d.) Formación Reticular y Fibras de Asociación del Experimental Encefálico. Departamento de anatomia facultad de medicina, UBA. [11]Le Scouarnec, R. P., Poirier, R. M. Owens, J. E., Gauthier, J., Taylor, A. G. and Foresman, P. A. (2001) Use of Binaural beat tapes for treatment on anxiety: a pilot study of tape preference and outcomes. Alternative Therapies in Health and Medicine. [12] Díaz, M. A., & Comeche, M. I. (2004). Beneficios de la relajación. Retrived from: http://www.psicologiadelasalud.es/beneficios_de_la_relajacion.html [13] Gómez García, J. (2003). Efectos de la música trance percusiva y la música trance electrónica en el EEG. Tesis Licenciatura. Psicología. Departamento de Psicología, Escuela de Ciencias Sociales, Universidad de las Américas Puebla. Retrieved from:
Hi Jason, thanks for all the uploads to youtube. I’ve been using them in work recently to help me concentrate and relax. I like the music tracks that you’ve chosen to overlay the tones. A couple of times in the last 2 weeks I’ve experienced the wavy pulse like sound, similar to the tones in my left ear. I wasn’t listening to tracks at the time or that day. It doesn’t last but it feels a bit strange. I wondered if I might have been listening to the tracks too loudly and that it was almost like a type of tinnitus. I’m curious to know if anyone has been in touch with you in the past to say they’ve had a similar experience?

Writing or talking about the things that prey on you—in a diary, with friends, in a support group or even a home computer file—helps you feel less alone and helpless. One study, published in The Journal of the American Medical Association, looked at people who had either rheumatoid arthritis or asthma— conditions known to be stress-sensitive. One group chronicled in a perfunctory manner the things they did each day. The other group was asked to write daily about what it was like, including fears and pain, to have their disease. What researchers found: People who wrote at length about their feelings had far fewer episodes of their illness.
I believe that there is a frequency at which a brain functions, they can vary depending on circadian rhythm or other factors. You can check the various effects on the brain caused by varying frequencies. Check this link -> Binaural beats. When we expose our brain to isochronic/binaural beats, it has a resonating effect on the brain, i.e. the brain starts to alter its frequency in order to synchronise with the tone. Once the specific frequency is achieved, you will have the desired effect (depending on the specific frequency you are trying to induce).
Without the additional cortisol in your system, your body can let go of excess stored fats and let you lose weight that may be causing heart problems and liver problems. This exercise also helps clear out your lymphatic system from toxins and waste and increases the oxygen flow within yourself. Both of these will give you more energy and boost your immune system.

From a brainwave entrainment effectiveness perspective, it’s my understanding that the response from isochronic tones stimulation starts to diminish over 30Hz and that 40Hz is about the limit for using them. So from what I’ve read on the topic a 100Hz beat wouldn’t work, probably because it’s too fast for the brain to process and synchronise with it.
Among the four dominant types of brainwaves, the Theta wave has earned the reputation of perhaps being the “most creative”. The dominant pattern when people are in the dream stages of their sleep, a person with increased Theta brainwaves during waking activity has a very high level of thinking and creativity. With a high amplitude and frequency of 4 Hz to 8 Hz, Theta waves are often dominant in the brain’s right hemisphere, which is also the hemisphere of highly-creative people. Here are some of the benefits you might enjoy with an increased Theta brainwave production:
LEARNING OBJECTIVE • Exercise can be an effective component of a stress management program, and all types of exercise can be beneficial for stress management. Exercise programs consistent with the current recommendations to improve health can be prescribed to manage stress. Fitness professionals should recognize that it might be necessary to refer a client to a psychologist or other health care provider to help develop strategies for managing stressors that produce chronic and acute episodic stress.
As Dawkins explains, ideas spread through the behavior that they produce in their hosts, which is what enables them to be transmitted from one brain to another. For example, an ideology — such as a religion — that causes its inhabitants to practice its rituals and communicate its beliefs will be transmitted to others. Successful ideas are those that are best able to spread themselves, while those that fail to self-replicate go extinct. In this way, some religious ideologies persist while others fade into oblivion.
Altered states of consciousness: In as early as 1987 it was discovered that photic stimulation at specific frequencies produced an altered state of consciousness. An extremely small study with just 4 individuals involved photic stimulation at 6 Hz, 10 Hz, and 18 Hz. The results were reported to have altered their conscious awareness. This really isn’t that surprising to anyone that’s used brainwave entrainment therapy.
I never do much to my hair, but I was ready to update my look a bit. I checked Yelp for some suggestions and I found Christopher Brian Salon. I called after work to make an appointment and they had an opening the next day. Perfect! I walk in and was greeted and offered a beverage. The salon is very sharp looking. I love the long mirrors, the light fixtures and beautiful art all around. When my stylist comes over, she introduced herself, Stacy.We go over my hair preferences and she gives me some options. We decide to try balayage. During my hair treatment, she is easy to talk to and funny. She even gave me a brief history of balayage, which I found pretty interesting. She really took the time to listen to my usual routine and suggested how I can change things in the future, but this was a great foundation to start. After my hair was colored and styled, she never pressured me to buy any add ons. Stacy was professional and kind during my time in the salon. My hair came out beautiful! I look forward to going back!!
As you close your eyes, this session quickly lulls you down into deep delta sleep, where the body recovers and grows. The session starts at a waking frequency, soon taking you down deep into a delta, with stops at the significant beneficial frequencies such as the de-stressing 10Hz, the grounding 7.83Hz Schumann resonance (SR), and the deeply relaxing 5.5Hz. You’ll soon find yourself in a deep, healing sleep. If you’re particularly stressed, try listening to Power Chill before starting.
There is no single relaxation technique that is best for everyone. The right relaxation technique is the one that resonates with you, fits your lifestyle, and is able to focus your mind and interrupt your everyday thoughts to elicit the relaxation response. You may even find that alternating or combining different techniques provides the best results. How you react to stress may also influence the relaxation technique that works best for you:
Tracks that move from alpha to theta can be a perfect vehicle for transitioning from a hectic day into a relaxing and rejuvenating sleep. Beginning with alpha waves takes you into a light but still alert meditative mind state where the difficulties of the day can be resolved and put to rest. Later, theta waves go deeper into the unconscious, preparing you for sleep and dreams.
The immobilization response. If you’ve experienced some type of trauma and tend to “freeze” or become “stuck” under stress, your challenge is to first rouse your nervous system to a fight or flight response (above) so you can employ the applicable stress relief techniques. To do this, choose physical activity that engages both your arms and legs, such as running, dancing, or tai chi, and perform it mindfully, focusing on the sensations in your limbs as you move.
Gamma waves are the most recently discovered brainwave, a discovery made possible by digital EEG technology. Gamma is associated with the integration of information from different areas of the brain, and having a good memory is associated with having a certain baseline of 40 hertz gamma activity. Low gamma activity is associated with learning disabilities and poor memory.
Isochronic tones have only been proven to have an effect while you are listening to them, that’s why you won’t find me claiming anywhere that there are potentially positive long-term effects. Once the tones stop, your brainwaves are no longer being stimulated by the sound and so they stop being in sync with the tone frequency. For you to think you are still feeling the effects after all this time and from such a short time listening to them, I think it may be linked to anxiety. I know that some people who are new to this type of thing can build up a strong feeling of anxiety, after worrying about the potential effects brought on by fear of the unknown. I suspect the problem may be psychological with you worrying about the potential effects and keep repeating the experience from memory in your head. When you keep going over the same thing in your head like that and worrying about it, it’s easy to then spot other potential side-effects like how your nostrils and body temp is feeling, then making links back to that experience and labelling that as the reason. I think the best way to overcome this is to realise that the side-effects you are mentioning are completely unrelated, so there is nothing to worry about. These tracks are literally listened to for millions of hours a month on YouTube across loads of channels. If the effects lasted for a long time people would just listen for 5 minutes and come back in a couple of weeks. But people keep coming back to listen because that’s the only way to feel the benefit and effects…while you are listening to them. If you are unable to stop thinking and worrying about this on our own, I recommend that you speak to your doctor about it or a specialist in dealing with anxiety issues. I hope that helps.
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Maya Mendoza is a published author of 3 personal development books. She has run an NLP / EFT Practice for 29 years helping clients transform problems into personal power. Maya is also a accomplished copywriter and well known Digital Marketing & Social Social Media Strategist - Specializing in Google+ for business. She was named "best marketing consultant" in Glasgow, UK in 2013.  
Then in my own research regarding my life-long hypertension and its resistance to medication, I became very concerned when I learned that 145/95 is the gateway to dementia. At that time my BP was consistently 145/95. Then, even worse, it started to become routinely 161/106. I was simply unwilling to take more medication with all its attendant side effects, so I started researching natural solutions. I became aware of a breathing apparatus which sold for $300 that would help me train myself to deep breathe, thereby reducing my blood pressure. $300 seemed like a lot, but not in the scheme of saving my life. I started thinking. I already knew how to breathe from my brief studies in Chi Gung. I simply needed something to help me focus my mind. I tried using the Chi Gung breathing while simply counting 200 breaths. It worked for a short while, but I quickly became far too bored, even though I knew it could be a lifesaving measure. I had been considering EquiSync for sometime, and realized it was much less expensive than a $300 breathing regulator, and that it might serve a dual purpose. So I purchased the entire suite.
“Mini-brains,”  or brain organoids, the latest development in stem cell technology, are organized 3D cell structures made up of different brain cells, which resemble the complexity of the human brain. Human stem cells can be  grown into brain organoids in 40 days, offering neuroscientists an  unprecedented opportunity to more accurately model human brain  development and disease. Until now, scientists had two choices: to study the brains of other mammals and extrapolate similarities with the human brain, or study the cells that make up the brain in a dish, which  although informative, can only tell us so much about how the human brain  works as a whole.
Writing or talking about the things that prey on you—in a diary, with friends, in a support group or even a home computer file—helps you feel less alone and helpless. One study, published in The Journal of the American Medical Association, looked at people who had either rheumatoid arthritis or asthma— conditions known to be stress-sensitive. One group chronicled in a perfunctory manner the things they did each day. The other group was asked to write daily about what it was like, including fears and pain, to have their disease. What researchers found: People who wrote at length about their feelings had far fewer episodes of their illness.
Headaches: There are several reports of brainwave entrainment providing therapeutic benefit for those suffering from general headaches or migraines. A study in 1985 analyzed photic stimulation within the theta range (5 Hz to 8 Hz) and discovered that this protocol provided significant headache relief. A total of 19/24 participants noted that the “slow wave” photic stimulation provided “complete relief” from chronic headaches and migraines.
Beta brainwaves are produced and associated with states where cognition, concentration and arousal are at their highest. These are commonly said to be at the peak of physical and mental activity. Unless a positive outlook is maintained then anxiousness, tension and paranoia can become issues. Beta is the common brainwave state for most adults in developed countries.
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First of all thank you for your amazing website, I have a question regarding these matters, I can make both binaural beats and isochronic tones for myself but I doubt for low frequencies states (Theta and Delta) which one is better? Because I searched a lot and saw that binaural beats are better for low frequencies and for high frequencies (Beta Gamma Lambda….) isochronic tones are more effective. Also, for Alpha states some said isochronic and other said binaural.

Since it’s humble beginnings, the science of brainwave entrainment has evolved to be one of the most potent and powerful ways to unlock the full potential of the human mind. Our audios have been created by brainwave entrainment engineer, Ashton Aiden, and his years of research, expertise, personal experience, and creativity. We are confident that the audios we offer on this site are of the best quality you will ever find, anywhere.
Binaural beats can be experienced in any float session you book.  To this point in your floating practice you may, or may not, have heard of – or perhaps already experienced – binaural beats and their effective use of being a unique option/tool to listen to while in (or out of) the tank. But what exactly are binaural beats, how do they work and why choose to listen to them? All good questions, so here we go:
Essentially, the brain is a biological computer, and an ideology is a set of coded instructions, or “cultural software,” that is running on the brain’s hardware. Esteemed philosopher and cognitive scientist Daniel Dennett insightfully described how ideas can control minds when he said, “The haven all memes depend on reaching is the human mind, but a human mind is itself an artifact created when memes restructure a human brain in order to make it a better habitat for memes.” In this regard, it is often not the brain that controls the mind, but the memes that compose the mind that control the brain. This is especially the case when the meme is a religion.
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