By this point, it seemed like organoids with a living blood supply looked more like a human brain in terms of structure than they had ever looked in a dish because they were able to survive long enough to develop properly. However, the question still remained as to whether the neurons and their synapses were functional. Neurons are electrically excitable cells that receive, process and transmit information through electrical  and chemical signals. Calcium plays an important role in the transmission of electrical signals from one neuron to the next. Changes  in the levels of calcium at the end of neurons can be measured using calcium-sensing proteins that light up red. When the scientists looked through the glass window in the skulls of the mice, they were able to see that neurons did have fluctuating levels of calcium, suggesting that  neurons in the brain organoids were active. To be sure, they used electrodes to directly measure the electrical activity of the implanted organoid at different places and during different times of development, and discovered that the neurons were able to electrically stimulate each  other and respond to stimuli from the external environment.The researchers had succeeded in creating fully functional brain organoids. Then things got really interesting.
Most massage therapists recommend getting a weekly massage, as this is the frequency that has shown the most significant benefit for most problems. However, even a monthly massage provides benefits. If you don’t have access to a good massage therapist, getting your muscles rubbed by a loved one works nearly as well. All it takes is a little bit of love to give a home-based massage. This can help connect you with your loved one, can act as a prelude for more intimate activities, and can build better bonds. A 15-minute foot massage from your husband has been reported to be one of the most intimate activities a husband and wife can share without engaging in sex.
With each pulsed tone, the brain produces an electrical response. The effects one experiences are the creations of the brains reaction to the “tones”, what neurologists call the “cortical evoked response” (the electrical response of the top most cortical layer of the brain). The brain is a mass of neurons, each taking part in storing, retrieving and transmitting electro-chemical impulses: information, colors, images, sounds, smells and tastes. Brainwave entrainment stimulates different areas of the brain allowing for the awakening and subsequent release of various levels of stored material. It also has an effect of  quietening the mind for clearer thought and process.
ADHD: In 1997, various researchers conducted a study testing whether children with ADHD (attention-deficit hyperactivity disorder) would benefit from audio-visual entrainment in a school setting. The researchers entrained a small sample of 34 students from 2 different schools. They were given audio-visual entrainment for a period of 1 month and 3 weeks at various times throughout the school day.
However, you can give yourself all of the nutrition of the produce in a very easy to drink package. This leaves you feeling light and energetic and gives your body a chance to digest the food quickly. It lets your body extract more vitamins and minerals from the juices you’re drinking, and your body’s demand for food goes down. You won’t feel hungry, and you won’t continually be looking for a snack or meal. You’ll just feel the rush of energy and healing properties from the fruits and vegetables.
Theta waves have a frequency between 4 and 7.5 hertz, making them slower than more wakeful alpha but faster than the dreamless slumber of delta. Theta brainwaves are the frequencies of nighttime dreams and REM sleep when the brain goes through bursts of activity and eye movement. People also experience theta waves in a state of light sleep, deep relaxation, during meditation and prayer, and when daydreaming. Theta waves produce an experience of inward wakefulness where we become disengaged from the outside world while engaging in inner activity. At the lower frequencies of theta, sleeping states are experienced, and at the higher range of frequency, awake relaxed states are experienced. 
Animals are used in research without us fully understanding their consciousness, so why should we worry about creating artificial 3D brain-like structures?  Maybe we shouldn’t. This is something we, both the scientific community and the public, need to work out. A variety of 3D organoids including a colon, small intestine, liver, retinal cells (cells in the eye), and pancreas have been implanted into living organisms, in some cases, to repair and rescue tissue damage (colon, liver, and pancreas). Meaning  that organoids may have potential for cell therapy. Stem cell therapy is  already being tested in a number of clinical trials, and organoids could be the next step. We are not that many steps away from organoids reaching a human brain, therefore, it is worth considering how they  impact the brains of other living creatures.
So how’s that novel coming? Your new song? What about that program you were going to write? Or the website you wanted to build? If your creative project, no matter what it is, isn’t coming along as smoothly or as quickly as you’d hoped, you’re not alone. After a lot of soul-searching, research, and banging my head against the wall, I've learned a lot about creative flow, and I'd like to share these tools, tactics, and insights with you. But back to where we started... It’s not that you didn’t … [Read more...]
Thanks for your appreciation of what I’m doing. I’ve been asked for help with autism a number of times over the years, so it’s something that I’ve often looked into and tried to find new information about. Unfortunately, I’ve yet to find any specific research relating to it and using the type of brainwave entrainment tones I use. There are a number of opinions and claims out here, but I’ve often found them to be conflicting. While some are recommending higher frequency gamma waves, others are recommending lower frequency alpha and theta waves while meditating.
If you're struggling to focus and feeling a bit tired and unmotivated while studying, you can help boost your concentration and energy levels by increasing Beta activity.  The SMR range is right at the bottom of the Beta range, so it's not too intense, and so is ideal for playing in the background and using as a general study aid.  If you are looking for something a bit higher for a more intense focus session, try my Study Focus isochronic tones session, which uses frequencies between 14-17Hz.

Binaural beats are created from two different continuous tones, which when sent separately to each ear create a single beat inside your head. Isochronic tones are basically a single tone which is switched on and off at regular intervals. Imagine a single continuous tone playing on a stereo system and you’ve got your hand on the volume switch. Then once per second, you turn the volume off for half a second and keep doing that every second. For half a second the volume is off, for the other half a beat waveform is formed. The beat is cycling once per second per second, i.e. at a rate of 1Hz.
A simple spinal twist can help you get a better night's sleep. It alleviates tension that's built up in your lower back throughout the day. Sitting on your bed with legs crossed, place your right hand down on the bed behind you and rest your left hand on your right knee. Sit up straight and inhale for four to eight counts, lengthening your spine as you breathe. On your exhale, begin to twist toward your right hand (don't strain your neck). Hold this position for four more full breaths, lengthening your spine on the inhales and deepening your twist on the exhales, if it feels comfortable. Repeat yoga asanas on opposite side. (These stress-reducing yoga poses also help calm anxiety.)
With its focus on full, cleansing breaths, deep breathing is a simple yet powerful relaxation technique. It’s easy to learn, can be practiced almost anywhere, and provides a quick way to get your stress levels in check. Deep breathing is the cornerstone of many other relaxation practices, too, and can be combined with other relaxing elements such as aromatherapy and music. While apps and audio downloads can guide you through the process, all you really need is a few minutes and a place to stretch out.

- Added the ability to create a playlist of your own iTunes library music and use it as the background. The behavior of the app when iTunes music is used instead of the included ambience is slightly different so please review the help. Notably, unlike our included ambience which can be played at a volume below the device volume, iTunes music can only be played at the device volume. So when playing iTunes music the Ambience volume slider disappears.
Proceedings of the 9th Conference on Interdisciplinary Musicology – CIM14. Berlin, Germany 2014 nature (birds and wind) while the second group listened to theta binaural sound waves. Both groups listened to the stimulus through headphones. During the experiment, participants were monitored with the Neurosky Mindwave Interface, which was connected through Processing to a Max Patch that saved all the data in a ‘.csv’ file. Before the stimulus, a baseline EEG took place and the participants answered the “Trait” part of the STAI test and a pre-experiment “State” version of the test. After the experiment, participants answered a post-experiment “State” STAI and a post-experiment EEG also took place. Each experiment was developed with one participant at a time in a controlled environment. American Psychological Association Ethical Principles and Code of Conduct 2002 were followed. 6. MATERIALS • Herman Miller chair • Neurosky Mindwave Interface • Maximum Voltage – 1mV • Maximum radiofrequency Range (Bluetooth) 10m • Maximum transference rate through RF – 250kb/s • Sample rate – 512Hz • Battery cycle – 6-8h • MacBook Pro 7. SOFTWARE • Processing 1.5.1 • Microsoft Excel • Max 6 • Braintocsv V1.5: Application developed in Max 6 by Santiago Rentería, which collates data gathered from the Mindwave interface into a ‘.csv’ file. 8. DOCUMENTS • STAI questionnaire (Annex 2) • STAI “Trait”: Measures anxiety as a temporal state. • STAI “State”: Measures anxiety based on how people feel on a daily basis. • Consent Letter (Annex 3) 9. CONTROL ENVIRONMENT Recording Studio Control Room located at Instituto Tecnológico y de Estudios Superiores de Monterrey, Campus Santa Fe. Fixed temperature at 22ºC and acoustically isolated. 10. STIMULI • Experimental group – Binaural Theta frequencies • Control group – Nature environmental sounds 11. PROCEDURE • The participant is asked to read and sign a consent letter. • A pre-experimental three-minute encephalogram is taken and the participant is required to answer State and Trait STAI tests. • The corresponding stimulus is played during ten minutes and an EEG is taken. • The State STAI test is answered and a post-experiment EEG is taken. 12. VISUAL DATA ANALYSIS The stimuli took place from second 180 to second 774. (Graphs in Annex 1) 12.1 Theta The significant time range was from second 3 to second 948. The most significant moments were the following: (see annex A1.5) s = 189; p = 0.014; t = 1.025 s = 495; p = 0.002; t = -1.923 s = 780; p = 0.001; t = -2.349 12.2 Meditation The significant time range was from second 240 to second 912. The most significant moments were the following: (see annex A1.3) s = 240; p = 0.042; t = .0.685 s = 522; p = 0.013; t = 0.546 s = 702; p = 0.016; t = 0.897 12.3 Delta The significant time range was from second 12 to second 954. The most significant moments were the following: (see annex A1.10) s = 177; p = 0.046; t = 1.696 s = 627; p = 0.016; t = -1.366 s = 912; p = 0.007; t = 1.758 12.4 Attention The significant time range was from second 243 to second 870. The most significant moments were the following: (see annex A1.11) s = 243; p = 0.021; t = 0.672 s = 513; p = 0.005; t = 0.722 s = 753; p = 0.017; t = 0.383 12.5 STAI Variations were found in STAI-State pre-experiment and post-experiment: • Control group results rose from 19 to 21 • Experimental group results decreased from 20 to 15. Variations between both groups were found in the STAI –Trait: • Experimental group with a score of 32 in STAI-T test outran control group by 4 points 13. RESULT ANALYSIS Samples were analyzed every three seconds. They were later statistically distributed according to the T-student test in order to find differences between both groups. For this experiment, the significant p value was p<0.05, this means that the probability is less than 5% T-student detailed analysis: • The meditation value is similar in both groups, (see graph A1.3). T-student function shows less significant points for this parameter. This means both stimuli induced relaxation to the participants. • Theta values are higher in the control group, especially after second 510 (see graph A1.5) almost at the middle of the stimulus. • STAI “State” post-experiment results from the experimental group are higher than the control. Therefore, theta binaural frequencies were more effective as an anxiolytic stimulus. (see graphs A1.1 and A1.2) • Delta values are higher after second 285 in the control group (see graph A1.10). This indicates deep sleep and losing of consciousness over the body (unconscious relaxation). It is highly possible that the participant fell asleep or got to the first stages of sleep. • There is a significant difference in delta between experimental and control groups after second 870 (post-stimulus). For the
Isochronic tones are basically just a single tone with the volume being turned on and off at regular intervals. When you apply the same effects to music or a noise, it’s usually referred to as amplitude entrainment effects (in Mind Workstation anyway). When you apply the on/off effect to music or noise it’s usually done by targeting a specific frequency range in the sound and only turning that part on/off, leaving the rest of the music/noise untouched. What that does is allow parts of the music/noise to play without being distorted/interrupted, making it sound more pleasant to listen to. It produces a kind of fluttering sound as I like to call it and you can adjust the level of intensity.
This plant, a relative of cabbage and broccoli, is native to Peru and is in the early stages of research that shows it helps fertility and sexual drive. It has historically been used by women to help them healthfully get through menopause. It’s a highly nutritious plant containing healthy carbs and lots of vitamins and minerals. The chief benefit for women going through menopause is it enhances sexual drive. Most women going through menopause find their desire for sex to be at an absolute minimum. It puts a lot of strain on their relationships and can cause mood swings. Maca can help increase your desire for intercourse and make it more comfortable when you have it.
Turns out, science says there is something to needing “fresh air”—even opening a window can help get more oxygen to your brain, soothing stress. “We live so much of our lives indoors, that when stress hits, one of my go-to techniques is to get outside or open a window,” Dr. Serani says. “Taking in a nice deep breath of crisp fresh air can immediately shift your neurochemistry.” If you’re overwhelmed with work, it can seem hard to take a break; but a quick step outside is even recommended by the American Psychological Association. When you come back, you’ll be recharged and ready to take on the challenge.
Anabel first called on Alakazam in Talking a Good Game! to help her and Ash when they were attacked by Team Rocket. Alakazam was able to beat them with its powerful Psychic attacks. Ash then realized that Anabel was a Frontier Brain and that he would have to battle Alakazam. Ash chose Corphish for the match. Anabel had the ability to telepathically communicate with her Pokémon and give commands without saying a word. In the end, Alakazam easily defeated Corphish. Alakazam then went on to defeat Ash's Tauros before finally being defeated by his Pikachu, but not before weakening it.
When stress attacks, it can feel like your whole world is crashing down. Remind yourself what’s good in your life with a quick gratitude round-up. “Studies show gratitude techniques like counting your blessings can be a significant stress reducer,” Dr. Serani says. “Gratitude research reports that those who utilize daily gratitude reflections have higher levels of positive emotions, life satisfaction, vitality, optimism, and lower levels of depression and stress.” Reminding yourself of the good things in life can put stress in perspective. “Studies show that cultivating an optimistic mindset can help you maintain a positive mood,” Whitaker says. “When you are positive and grateful, you are able to handle difficult situations better.” Just look out for these stress relievers that actually backfire.

When you're having a hell of a day—good or bad—checking out for 10-15 minutes is revitalizing. Find a place where you can be alone (and definitely ditch the cell phone)—the attic, the bathroom, a quiet cafe, a big oak tree—and wipe the slate clean for a few minutes. Do whatever it is that relaxes you: Meditate, read a novel, sing or sip tea. It's crucial to take just a few minutes everyday to de-stress. It's not how much time you allot, but being consistent that's important.

The exact physiological mechanisms to explain how exercise improves stress have not been delineated. Human and animal research indicates that being physically active improves the way the body handles stress because of changes in the hormone responses, and that exercise affects neurotransmitters in the brain such as dopamine and serotonin that affect mood and behaviors (9,11). In addition to the possible physiological mechanisms, there also is the possibility that exercise serves as a time-out or break from one’s stressors. A study that tested the time-out hypothesis used a protocol that had participants exercise but did not allow a break from stress during the exercise session (5). Participants were college-aged women who reported that studying was their biggest stressor. Self-report of stress and anxiety symptoms was assessed with a standard questionnaire before and after four conditions over 4 days. The conditions were quiet rest, study, exercise, and studying while exercising. These conditions were counterbalanced across participants, and each condition was 40 minutes in duration. The “exercise only” condition had the greatest calming effect (5). When participants were not given a break from their stressor in the “studying while exercising” condition, exercise did not have the same calming effect.
I have never been more creative, productive, more loving to all people nor have I ever been happier in my life. All the wisdom I have found in my pursuit of happiness was somewhere in my intellect. Now it is a part of me. I am using it. I now consider myself a model for younger people to let them see how it is possible to function and be everything they’ve wanted to be. I just celebrated my 85th birthday and I am as young as when I was 25. Thank you for giving me the gift of my true self.
Because of the way they are created, there may be a positive benefit from listening to binaural beats without considering the brainwave entrainment aspect, but I haven’t seen any research on that. I first discovered brainwave entrainment through binaural beats about 10 years ago now, but they didn’t do anything for me. So I’ve never been a regular user of them. I believe isochronic tones are a more effective way to produce hemispheric synchronisation because they produce a much stronger response in the brain

You can practice visualization on your own or with a therapist (or an app or audio download of a therapist) guiding you through the imagery. You can also choose to do your visualization in silence or use listening aids, such as soothing music or a sound machine or a recording that matches your chosen setting: €”the sound of ocean waves if you’ve chosen a beach, for example.
In addition to its calming physical effects, the relaxation response also increases energy and focus, combats illness, relieves aches and pains, heightens problem-solving abilities, and boosts motivation and productivity. Best of all, anyone can reap these benefits with regular practice. And while you may choose to pay for a professional massage or acupuncture session, for example, most relaxation techniques can be done on your own or with the aid of free audio downloads or inexpensive smartphone apps.
Need a quick breather? Stressed to the max but haven’t got time to meditate? Then this 10 minute brainwave entrainment is the one for you! You will hear the gentle waves of the beach and sea gulls calling out, but underneath is a short 10 Hz relaxation session, ideal for stress relief or as a quick break from daily worries. Can be used with headphones or speakers.
In the 1980s, a researcher in Japan, Tsuyoshi Inouye described how light stimulation creates synchronization of brain hemispheres. Since then, other researchers have detailed the positive effects of hemispheric synchronization including a 1984 study by researcher Dr. Gene W. Brockopp stating that hemispheric synchronization resulted in improved intellectual functioning as well as improvements in long-term memory, and these effects are cumulative over time.
Well, I finally listened to “Equisync III” after listening to “Equisync I” & the “Equisync II” several times. Let me just say that this put me in another state of consciousness within 7 minutes(guessing) it was beautiful! I meditated throughout the entire 70 minute CD set! It didn’t feel like 70 minutes. I could feel energy in my neck, my solar plexus area and at the brow of my head! Definitely NOT for beginners!
In physics, entrainment is the process of two oscillating systems coming to assume the same periodic rhythm, such as is observed when two clocks slowly synchronize their ticking and tick together in harmony after some time. Pendulums also achieve this same synchronicity when swinging in close proximity to one another, a phenomenon first observed and written about in 1665 by Christiaan Huygens, a Dutch scientist.
Behavior problems: In two separate studies with a total of 57 children, it was found that brainwave entrainment was able to significantly improve behavior problems. One of these studies was conducted on children with ADHD and determined that they significantly improved not only in regards to attention deficits, but also in their behavior. Both parents and teachers reported statistically significant improvements in how the children behaved.
For many of us, relaxation means zoning out in front of the TV at the end of a stressful day. But this does little to reduce the damaging effects of stress. To effectively combat stress, we need to activate the body’s natural relaxation response. You can do this by practicing relaxation techniques such as deep breathing, meditation, rhythmic exercise, and yoga. Fitting these activities into your life can help reduce everyday stress, boost your energy and mood, and improve your mental and physical health.
Practitioners are discovering a number of different areas in which entrainment therapy may bring positive benefits. From managing mental health more effectively through to providing increased mental focus and concentration, it is thought the technique can be adapted according to the specific issues being treated. An improved immune system, enhanced levels of pain management, and a reduction in autoimmune disorders are also thought to be achieved through the therapy, leading many individuals with chronic ill health to consider brainwave entrainment as a non-invasive yet effective therapy.

In the average person, the activity of one brain hemisphere is dominant over the other, called brain lateralization. This hemispheric imbalance leads us to experience the world in a black and white way, perceiving separation over connectedness. When brainwave entrainment is used to synchronize brainwave activity in both hemispheres simultaneously, a person can more easily integrate information from all parts of the brain and solve problems with greater intelligence and sensitivity.
Theta brainwaves are produced and associated with states of deep relaxation and meditation. They are also associated with the state of lucid dreaming and NREM sleep. In Theta creative inspiration and enhanced powers of visualization also come. The state of deep relaxation combined with the state where the mind is better attuned to absorbing knowledge, hence it brings the super learning state. Theta is incredibly good for stress relief and release too.
Proceedings of the 9th Conference on Interdisciplinary Musicology – CIM14. Berlin, Germany 2014 http://catarina.udlap.mx/u_dl_a/tales/documentos/lps/gomez_g_j/capitulo_1.html [14] Universidad Complutense de Madrid. (2006). Proyecto de apoyo a la evaluación psicológica clínica. Retrieved from http://pendientedemigracion.ucm.es/info/psclinic/evaluacion/Proyecto Apoyo EPC 2006/INSTRUMENTOS EVALUACION/TRASTORNOS DE ANSIEDAD/EVALUACION GENERAL DE LOS TRASTORNOS DE ANSIEDAD/ESCALA DE ANSIEDAD ESTADORASGO (STAI)/STAI_P.pdf [15] Universidad Complutense de Madrid. (2006). Proyecto de apoyo a la evaluación psicológica clínica. Retrieved from http://pendientedemigracion.ucm.es/info/psclinic/evaluacion/Proyecto Apoyo EPC 2006/INSTRUMENTOS EVALUACION/TRASTORNOS DE ANSIEDAD/EVALUACION GENERAL DE LOS TRASTORNOS DE ANSIEDAD/ESCALA DE ANSIEDAD ESTADORASGO (STAI)/STAI_F.pdf [16] Hassan, H., Murat, Z., Ross, V., & Buniyamin, N. (2012). A Preliminary Study on the Effects of Music on Human Brainwaves. International Conference on Control, Automation and Information Sciences (ICCAIS) [17] Johnson, J., Petsche, H., Richter, P., Von Stein, A., & Fiilz, O. (1996). The Dependence of Coherence Estimates of Spontaneous EEG on Gender and Music Training. University of California Press. Annexes: https://www.mediafire.com/?cayel53iabg620d
This session shifts from the 14Hz sensormotor rhythm through beta to 40Hz gamma, and repeats the pattern over and over, constantly “revving up”the mind with each repetition. The process is stabilized with a 10Hz background alpha beat, allowing the brain a place to relax instantly, whenever a let up allows. Use this session any time, and for as long as required to get the job done. Take in a High Energy Espresso on long-hauls for a welcome lift. Works without headphones, but the best benefits can be found with them. The session finishes at a fast, revving 18Hz beta. For use mainly with eyes open, engaged in activity - with benefit to be gained from periodically closing your eyes briefly and relaxing.
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