In their earlier experiments, the scientists had detected connections between neurons from organoids and neurons from the mouse brain, but they could not tell  whether or not the neurons could actually communicate with one and  other. Optogenetics is an extremely clever technique that uses light to  control neurons. By using this technique, the researchers were able to  specifically stimulate the neurons in the organoids by turning on and  off a light. When the light was on, the neurons of the organoids became  electrically active. When they used electrodes to measure the activity  of neurons outside the organoid in another part of the mouse brain, they  were able to detect electrically activated neurons there too, showing  that organoid neurons could signal to host neurons.


Hi Ulka, thanks for your compliment on my article. Unfortunately, I haven’t come across any studies or much discussion about the problem with habituation and isochronic tones and how to overcome it. The consensus among experienced users is to regularly change the frequencies and music soundtracks you listen to. Adding music to the tones does change the waveform you are stimulated with, so that’s one of the main reasons why I provide different soundtracks for my isochronic tones sessions. I have released some tracks which use amplitude modulations in the music, instead of isochronic tones. It might be worth giving them a try if you haven’t already. I have them in a playlist on YouTube https://www.youtube.com/watch?v=Lj5tHl2cuWw&list=PLveg0IEcZWN6OIRZyLkv0BJADY7Q6xFCl.
A popular opinion in the brainwave entrainment community is that listening to isochronic tones without music produces a much stronger effect.  However, in the study by Doherty, Cormac. “A comparison of alpha brainwave entrainment, with and without musical accompaniment” (2014),  it was concluded that brainwave entrainment was equally effective for isochronic tones, both with and without music.
PMS: There is a little research that supports the efficacy of brainwave entrainment for PMS symptom reduction in women. Women with long-standing and severe forms of PMS were administered photic stimulations for a series of 3 menstrual cycles. Following the photic stimulation, it was noted that women reported 64% improvement by the second menstrual cycle and 76% improvement after all three cycles.
It's tempting to reach for a cheeseburger when stressed, but go green at lunch instead. "Green leafy vegetables like spinach contain folate, which produces dopamine, a pleasure-inducing brain chemical, helping you keep calm," says Heather Mangieri, RDN, a spokesperson for the Academy of Nutrition and Dietetics. A 2012 study in the Journal of Affective Disorders of 2,800 middle-aged and elderly people and found those who consumed the most folate had a lower risk of depression symptoms than those who took in the least. And, a 2013 study from the University of Otago found that college students tended to feel calmer, happier, and more energetic on days they ate more fruits and veggies. It can be hard to tell which came first—upbeat thoughts or healthy eating—but the researchers found that healthy eating seemed to predict a positive mood the next day.
Applying brainwave entrainment in the alpha range may result in benefits similarly found with Zen or Transcendental Meditation. These benefits extend throughout the body and include improved breathing patterns, higher physical energy levels, an improved outlook, increased sports performance, improved relationships, and increased workplace satisfaction and performance … just to name a few.
Additionally, this root may help you lose weight and feel more energetic. Women who take maca find they have a bit more energy and fewer aches and pains. Maca is popularly included in sports drinks and nootropics that help improve athletic performance. Much of the research has been done on men, in regards to athletic performance using maca, but studies have also shown women benefit as much or even more. Finally, it may help you stabilize your emotions. Specific studies have shown that maca can help relieve the symptoms of mild depression and mood swings.
After one month of using Equisync, I feel relaxed, calm and not stressed at all, despite that I am leaving my present job soon for an early retirement, I handle the situation very well. I have the feeling that I’m going to be ok and there is nothing to worry about. This is what I have gained so far from using Equisync and it’s really meaningful in the erratic world that we live in.
My relaxation program calms your mind and relaxes your body without making you drowsy. You can use the full one hour program whenever you’d like to ease your stress and anxiety, and regain your mental focus. The program also includes a short 10 minute “instant mental refresher” for when you need a quick break from a hectic day. This program is designed for anyone suffering from constant stress and anxiety so that you can…

Theta stimulation: There appears to be no benefit associated with using theta stimulation for cognitive functioning, mood, or stress relief. While theta may be a useful way to induce sleep or alter your state of consciousness, there really isn’t much science supporting entrainment in this particular range for most purposes. Photic stimulation of theta between 5 Hz and 7 Hz can be useful for headaches.


For a few minutes a day, practice being mindful—focusing only on what's going on in the present —whether it's during your workout or taking a break from your work. Try taking a short walk and instead of thinking about what's worrying you, pay attention to your senses—what you see, feel, hear, smell. This can make a huge difference in your emotional and physical well-being when done daily.
Physical activity can pump up your feel-good endorphins and other natural neural chemicals that enhance your sense of well-being. Exercise can also refocus your mind on your body's movements, which can improve your mood and help the day's irritations fade away. Consider walking, jogging, gardening, housecleaning, biking, swimming, weightlifting or anything else that gets you active.
“Mini-brains,”  or brain organoids, the latest development in stem cell technology, are organized 3D cell structures made up of different brain cells, which resemble the complexity of the human brain. Human stem cells can be  grown into brain organoids in 40 days, offering neuroscientists an  unprecedented opportunity to more accurately model human brain  development and disease. Until now, scientists had two choices: to study the brains of other mammals and extrapolate similarities with the human brain, or study the cells that make up the brain in a dish, which  although informative, can only tell us so much about how the human brain  works as a whole.
With these studies in mind, EquiSync's revolutionary, multi-layered, multi-tiered approach was born. Designed to synchronize and harmonize your brainwaves while allowing you access to the deepest, most pleasurable, most beneficial states of meditation — much faster than the traditional route, EquiSync® has made mastering meditation easier than ever!

I have never been more creative, productive, more loving to all people nor have I ever been happier in my life. All the wisdom I have found in my pursuit of happiness was somewhere in my intellect. Now it is a part of me. I am using it. I now consider myself a model for younger people to let them see how it is possible to function and be everything they’ve wanted to be. I just celebrated my 85th birthday and I am as young as when I was 25. Thank you for giving me the gift of my true self.

Because of the way they are created, there may be a positive benefit from listening to binaural beats without considering the brainwave entrainment aspect, but I haven’t seen any research on that. I first discovered brainwave entrainment through binaural beats about 10 years ago now, but they didn’t do anything for me. So I’ve never been a regular user of them. I believe isochronic tones are a more effective way to produce hemispheric synchronisation because they produce a much stronger response in the brain
Discovered by Austrian Psychiatrist Hans Berger in 1908, Alpha brainwaves cycle 8 to 13 times per second, a good bit slower than beta brainwaves. While considered a part of a group of brainwaves, the Alpha brainwave has one distinct trait that makes it stand out from its siblings – it appears and disappears while going through our brain. Sometimes alpha waves are present, sometimes they are not. The disappearance of the Alpha brainwave usually occurs when someone is asleep or experiences heightened emotions such as fear or anger. This brainwave only appears whenever a person is awake and relaxed, a one-of-a-kind distinction among other types of brainwaves. 
Dissociative but not present. In college I started having difficulty with reading comprehension/absorption (not dyslexia, I could read everything out loud easily but not gather the meaning). Over the past two years or so, my memory has been concerning, as I am not middle or late aged. Since it had been getting worse, I have been researching for several years now for a cure. Biofeedback led me to neurofeedback (which I can’t afford at the moment).
For many of us, relaxation means zoning out in front of the TV at the end of a stressful day. But this does little to reduce the damaging effects of stress. To effectively combat stress, we need to activate the body’s natural relaxation response. You can do this by practicing relaxation techniques such as deep breathing, meditation, rhythmic exercise, and yoga. Fitting these activities into your life can help reduce everyday stress, boost your energy and mood, and improve your mental and physical health.
John and Doug discuss how to be a better you - how you should always be available to what you can learn. You have to show up to whatever you experience and do the best you can do in that moment. For John, his daily practice helped improve 30% in spirituality, in health, and in mental intelligence. A person can become a champion as they continue to practice. Discipline and motivation increases - it becomes deeper. When you learn about practice, you can accomplish way beyond what you thought … [Read more...]
This music encourages a state of alpha relaxation. The alpha state is a pleasant state of relaxed alertness. It’s a state that many people experience when they are waking up in the morning or when they are just beginning to drift off to sleep at night. While in a state of alpha relaxation, the mind is quite clear and receptive to information, learning is accelerated and one’s sense of creativity is enhanced. The mind is also very open to positive suggestions during this state.
John and Doug talk about iAwake Technologies' new track developed by Doug Prater himself, Stealing Flow - a tool which can help you become your best self. They also discuss Stealing Fire, the book which was the inspiration for Stealing Flow. John also talks about depression and how to overcome it through finding your path and your purpose - and how being in flow states facilitates that. … [Read more...]
Recently developed entrainment software has been designed to correct specific imbalances in hemispheric activity associated with undesirable mind-states. For example, people suffering with depression often have more activity in the right hemisphere, and specially designed brainwave music decreases this activity while increasing activity in the left hemisphere, reducing depression.
* Headphones/Earbuds are Required for Binaural Tones to be Effective as the Left Ear and Right Ear Audio must be isolated for the Brain to perceive the inaudible low-frequency difference between the two sides. ** Changes to Orientation Support: With the upcoming arrival of several new devices with new screen-sizes and aspect ratios, iOS 8 required a re-write of our iPhone and iPad UI to support these devices, and as part of that, we have returned the app to a Portrait-only view for now. Once we know what these future screen dimensions and Aspect Ratios are, and have time to work with the real devices, we can implement a new Landscape UI for the iPad.

They are a useful and effective tool that allow you a structured means in which to entrain your brain into a desired, new brainwave state using an intended set frequency range of the audio track. Frequency ranges for desired sleep, recovery and deep meditation states to different/higher frequency ranges for performance “flow-states” and high-level focus and calculation.


Since it’s humble beginnings, the science of brainwave entrainment has evolved to be one of the most potent and powerful ways to unlock the full potential of the human mind. Our audios have been created by brainwave entrainment engineer, Ashton Aiden, and his years of research, expertise, personal experience, and creativity. We are confident that the audios we offer on this site are of the best quality you will ever find, anywhere.
Need a quick breather? Stressed to the max but haven’t got time to meditate? Then this 10 minute brainwave entrainment is the one for you! You will hear the gentle waves of the beach and sea gulls calling out, but underneath is a short 10 Hz relaxation session, ideal for stress relief or as a quick break from daily worries. Can be used with headphones or speakers.
John and Doug discuss how to be a better you - how you should always be available to what you can learn. You have to show up to whatever you experience and do the best you can do in that moment. For John, his daily practice helped improve 30% in spirituality, in health, and in mental intelligence. A person can become a champion as they continue to practice. Discipline and motivation increases - it becomes deeper. When you learn about practice, you can accomplish way beyond what you thought … [Read more...]
The benefits of aerobic exercise — like running, dancing, spinning, and in-line roller-skating — include an increased heart rate. When your heart rate is accelerated, your body releases endorphins, natural opiates that make you feel good with no side effects. High-energy activities help you feel better physically and mentally. Just be sure to check with your doctor before starting any high-intensity workouts.
When the brain is stimulated with pulsed sounds (neuro-electrical activity via the nerves originating from the ears), the overall activity of the brain will respond to and align with these pulses. By selecting the desired rate, the brain — via the frequency following response (entrainment) — can be naturally induced towards the selected brainwave state.
Flaxseed, pumpkin seeds, and sunflower seeds are all great sources of magnesium (as are leafy greens, yogurt, nuts, and fish). Loading up on the mineral may help regulate emotions. "Magnesium has been shown to help alleviate depression, fatigue, and irritability," Sass says. "Bonus: When you're feeling especially irritable during that time of the month, the mineral also helps to fight PMS symptoms, including cramps and water retention."
The Transparent Corp forum – This forum is an invaluable resource for any brainwave entrainment user or enthusiast.  Most of the feedback is obviously focused on the Transparent Corp software, but with over 20,000+ posts now you can find answers to the whole array of brainwave entrainment questions on there.  (UPDATE: Sadly, the Transparent Corp forum has now been taken offline)
Different states of mind are associated with specific brainwave frequencies that would be inaudible if played directly. These frequencies can be induced in the brain indirectly by playing two different audible tones into each ear, which after being processed by the brain, are perceived as an inaudible beat matching the target brainwave frequency. As you listen, your own brainwaves fall into step with this inaudible beat, and after a few minutes synchronize with the target brainwave frequency. Brain Wave's 35 programs layer these binaural sequences into multi-stage sessions that have helped thousands of people focus and concentrate, feel positive and motivated, and sleep more soundly.
Like genes and gene complexes, when an ideology is replicated—or passed from one person or group to another — it undergoes mutations. As a consequence, different versions of that belief system are produced, which generate different types of behavior. As such, there are often good and bad variants of any given religion. For instance, there are moderate versions of Christianity and Islam, that promote qualities like a sense of community and a moral code that fosters ethical behavior. These ideas can be beneficial to the host organism, i.e., the religious-practicing individual. At the same time, there are harmful variants of Islam and Christianity — specifically the rigid fundamentalist versions — that cause the host mind to process information in a biased way, think irrationally, and become delusional.
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